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Articles (47)
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Use of ENABL® adjuvant to increase the potency of an adenovirus-vectored foot-and-mouth disease virus serotype A subunit vaccine

Barrera, José, Schutta, Christopher, Pisano, Melia, Grubman, Marvin J., Brake, David A., Miller, Timothy, Kamicker, Barbara J., Olutunmbi, Femi, Ettyreddy, Damodar, Brough, Douglas E., Butman, Bryan T

Journal:

Vaccine

Année:

2018

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2018

Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization

Keisuke Mori, Elia Duh, Peter Gehlbach, Akira Ando, Kyoichi Takahashi, Joel Pearlman, Keiko Mori, Hoseong S. Yang, Donald J. Zack, Damodar Ettyreddy, Douglas E. Brough, Lisa L. Wei, Peter A. Campochia

Journal:

Journal of Cellular Physiology

Année:

2001

Langue:

english

Fichier:

PDF, 935 KB

english, 2001

Rescue and production of vaccine and therapeutic adenovirus vectors expressing inhibitory transgenes

Jason G. D. Gall, Alena Lizonova, Damodar EttyReddy, Duncan McVey, Mohammed Zuber, Imre Kovesdi, Barbara Aughtman, C. Richter King, Douglas E. Brough

Journal:

Molecular Biotechnology

Année:

2007

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2007

Adenoviral vectors for gene transfer

Imre Kovesdi, Douglas E Brough, Joseph T Bruder, Thomas J Wickham

Journal:

Current Opinion in Biotechnology

Année:

1997

Langue:

english

Fichier:

PDF, 939 KB

english, 1997

Resistance to therapy caused by intragenic deletion in BRCA2

Edwards, Stacey L., Brough, Rachel, Lord, Christopher J., Natrajan, Rachael, Vatcheva, Radost, Levine, Douglas A., Boyd, Jeff, Reis-Filho, Jorge S., Ashworth, Alan

Journal:

Nature

Année:

2008

Langue:

english

Fichier:

PDF, 795 KB

english, 2008

Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

Wickham, Thomas J., Roelvink, Peter W., Brough, Douglas E., Kovesdi, Imre

Journal:

Nature Biotechnology

Année:

1996

Fichier:

PDF, 637 KB

1996

Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals

Izumikawa, Masahiko, Minoda, Ryosei, Kawamoto, Kohei, Abrashkin, Karen A, Swiderski, Donald L, Dolan, David F, Brough, Douglas E, Raphael, Yehoash

Journal:

Nature Medicine

Année:

2005

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2005

TNFerade Biologic: Preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene

Rasmussen, Henrik, Rasmussen, Camilla, Lempicki, Maria, Durham, Rebecca, Brough, Douglas, King, C Richter, Weichselbaum, Ralph

Journal:

Cancer Gene Therapy

Année:

2002

Langue:

english

Fichier:

PDF, 243 KB

english, 2002

Multiple Functions of the Adenovirus DNA-Binding Protein Are Required for Efficient Viral DNA Synthesis

Douglas E. Brough, Gustavo Droguett, Marshall S. Horwitz, Daniel F. Klessig

Journal:

Virology

Année:

1993

Fichier:

PDF, 932 KB

1993

Phosphorylation of the Adenovirus DNA-Binding Protein and Epitope Mapping of Monoclonal Antibodies against It

Vaughn Cleghon, Alejandra Piderit, Douglas E. Brough, Daniel F. Klessig

Journal:

Virology

Année:

1993

Fichier:

PDF, 874 KB

1993

Identification of a High-Molecular-Weight Cellular Protein Complex Containing the Adenovirus DNA Binding Protein

Joseph W. Ricigliano, Douglas E. Brough, Daniel F. Klessig

Journal:

Virology

Année:

1994

Fichier:

PDF, 1.07 MB

1994

Characterization of adenovirus type 5 insertion and deletion mutants encoding altered DNA binding proteins

Hans L. Vos, Douglas E. Brough, Frédérique M. Van Der^Lee, Rob C. Hoeben, Gijs F.M. Verheijden, Dennis Dooijes, Daniel F. Klessig, John S. Sussenbach

Journal:

Virology

Année:

1989

Langue:

english

Fichier:

PDF, 753 KB

english, 1989

Construction, characterization, and utilization of cell lines which inducibly express the adenovirus DNA-binding protein

Douglas E. Brough, Vaughn Cleghon, Daniel F. Klessig

Journal:

Virology

Année:

1992

Langue:

english

Fichier:

PDF, 1.98 MB

english, 1992

Isolation of RNA from residual BD SurePath™ liquid-based cytology specimens and detection of HPV E6/E7 mRNA using the PreTect™ HPV-Proofer assay

Eric P. Dixon, Lorraine M. King, Melissa D. Adams, Petter Grønn, Patricia G. Murphy, Charlotte A. Brown, George H. Brough, Hanne Skomedal, Douglas P. Malinowski, Timothy J. Fischer

Journal:

Journal of Virological Methods

Année:

2008

Langue:

english

Fichier:

PDF, 124 KB

english, 2008

Pharmacodynamics of adenovector distribution within the inner ear tissues of the mouse

Mark Praetorius, Kim Baker, Douglas E. Brough, Peter Plinkert, Hinrich Staecker

Journal:

Hearing Research

Année:

2007

Langue:

english

Fichier:

PDF, 417 KB

english, 2007

Adenoviral vectors for improved gene delivery to the inner ear

Mark Praetorius, Douglas E. Brough, Chi Hsu, Peter K. Plinkert, Susanna C. Pfannenstiel, Hinrich Staecker

Journal:

Hearing Research

Année:

2009

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2009

Development of gene therapy for inner ear disease: Using bilateral vestibular hypofunction as a vehicle for translational research

Hinrich Staecker, Mark Praetorius, Douglas E. Brough

Journal:

Hearing Research

Année:

2011

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2011

Novel adenovirus vaccine vectors based on the enteric-tropic serotype 41

Franck Lemiale, Hedi Haddada, Gary J. Nabel, Douglas E. Brough, C. Richter King, Jason G.D. Gall

Journal:

Vaccine

Année:

2007

Langue:

english

Fichier:

PDF, 937 KB

english, 2007

Canalostomy as a Surgical Approach for Cochlear Gene Therapy in the Rat

Gassner, Davina, Durham, Dianne, Pfannenstiel, Susanna C., Brough, Douglas E., Staecker, Hinrich

Journal:

The Anatomical Record Advances in Integrative Anatomy and Evolutionary Biology

Année:

2012

Langue:

english

Fichier:

PDF, 819 KB

english, 2012

Characterization of human adenovirus 35 and derivation of complex vectors

Duncan McVey, Mohammed Zuber, Damodar EttyReddy, Christopher D Reiter, Douglas E Brough, Gary J Nabel, C Richter King, Jason G D Gall

Journal:

Virology Journal

Année:

2010

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2010

Adenoviruses isolated from wild gorillas are closely related to human species C viruses

Duncan, McVey, Cranfield, Michael R., Torano, Holly, Kuete, Hubert M., Lee, Grace P., Glenn, Andrew, Bruder, Joseph T., Rangel, David, Brough, Douglas E., Gall, Jason G.

Journal:

Virology

Année:

2013

Langue:

english

Fichier:

PDF, 717 KB

english, 2013

Genetic Vaccine for Respiratory Syncytial Virus Provides Protection Without Disease Potentiation

Johnson, Teresa R, Rangel, David, Graham, Barney S, Brough, Douglas E, Gall, Jason G

Journal:

Molecular Therapy

Année:

2014

Langue:

english

Fichier:

PDF, 1.65 MB

english, 2014

Bcl-2 Gene Therapy Prevents Aminoglycoside-Induced Degeneration of Auditory and Vestibular Hair Cells

Pfannenstiel, Susanna C., Praetorius, Mark, Plinkert, Peter K., Brough, Douglas E., Staecker, Hinrich

Journal:

Audiology & Neuro-Otology

Année:

2009

Langue:

english

Fichier:

PDF, 917 KB

english, 2009

ORNITHOSIS IN TWO RAILWAY GUARDS AN OCCUPATIONAL HAZARD

Dew, John, Mawson, Kenneth, Ellman, Philip, Brough, Douglas

Journal:

The Lancet

Année:

1960

Langue:

english

Fichier:

PDF, 362 KB

english, 1960

Drug delivery to the inner ear using gene therapy

Staecker, Hinrich, Brough, Douglas E., Praetorius, Mark, Baker, Kim

Journal:

Otolaryngologic Clinics of North America

Année:

2004

Langue:

english

Fichier:

PDF, 460 KB

english, 2004

Optimizing atoh1-induced vestibular hair cell regeneration

Staecker, Hinrich, Schlecker, Christina, Kraft, Shannon, Praetorius, Mark, Hsu, Chi, Brough, Douglas E.

Journal:

The Laryngoscope

Année:

2014

Langue:

english

Fichier:

PDF, 591 KB

english, 2014

Atoh1 induces auditory hair cell recovery in mice after ototoxic injury

Kraft, Shannon, Hsu, Chi, Brough, Douglas E., Staecker, Hinrich

Journal:

The Laryngoscope

Année:

2013

Langue:

english

Fichier:

PDF, 709 KB

english, 2013

Improved Production of Adenovirus Vectors Expressing Apoptotic Transgenes

Bruder, Joseph T., Appiah, Angela, Kirkman, Wayne M., Chen, Ping, Tian, Jie, Reddy, Damodar, Brough, Douglas E., Lizonova, Alena, Kovesdi, Imre

Journal:

Human Gene Therapy

Année:

2000

Langue:

english

Fichier:

PDF, 861 KB

english, 2000

Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing

Small, Ben G, McColl, Barry W, Allmendinger, Richard, Pahle, Jürgen, López-Castejón, Gloria, Rothwell, Nancy J, Knowles, Joshua, Mendes, Pedro, Brough, David, Kell, Douglas B

Journal:

Nature Chemical Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1018 KB

english, 2011

175. Delivery Via Non-Viral Options to the Auditory Structures

Praetorius, Mark J., Klingmann, Christoph, Brough, Douglas E., Plinkert, Peter K., Staecker, Hinrich

Journal:

Molecular Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 83 KB

english, 2006

832. Efficient Readministration of Adenovectors to the Inner Ear

Staecker, Hinrich, Praetorius, Mark, Hsu, Chi, Brough, Douglas E.

Journal:

Molecular Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 97 KB

english, 2006

Adenovirus serotype 5-vectored foot-and-mouth disease subunit vaccines: the first decade

Grubman, Marvin J, Moraes, Mauro P, Schutta, Christopher, Barrera, Jose, Neilan, John, Ettyreddy, Damodar, Butman, Bryan T, Brough, Douglas E, Brake, David A

Journal:

Future Virology

Année:

2010

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2010

Use of Cryopreserved Cells for Enabling Greater Flexibility in Compound Profiling

Wigglesworth, M.J., Lawless, K.J., Standing, D.J., Mackenzie, E.K., Kitchen, V.R., Mckay, F., Ward, E., Brough, S.J., Stylianou, M., Jewitt, F.R., Mclaren-Douglas, A.M., Jowet, M.I., Tamayama, N., Fin

Journal:

Journal of Biomolecular Screening

Année:

2008

Langue:

english

Fichier:

PDF, 513 KB

english, 2008

Adenovector-mediated hair cell regeneration is affected by promoter type

Praetorius, Mark, Hsu, Chi, Baker, Kim, Brough, Douglas E., Plinkert, Peter, Staecker, Hinrich

Journal:

Acta Oto-Laryngologica

Année:

2010

Langue:

english

Fichier:

PDF, 363 KB

english, 2010

Repeat Administration of Proteins to the Eye With a Single Intraocular Injection of an Adenovirus Vector

McVey, Duncan, Hamilton, Melissa M, Hsu, Chi, King, C Richter, Brough, Douglas E, Wei, Lisa L

Journal:

Molecular Therapy

Année:

2008

Langue:

english

Fichier:

PDF, 312 KB

english, 2008

Persistent Expression of PEDF in the Eye Using High-capacity Adenovectors

Chen, Ping, Hamilton, Melissa, Thomas, Charles A, Kroeger, Kurt, Carrion, Miguel, MacGill, Randall S, Gehlbach, Peter, Brough, Douglas E, Wei, Lisa L, King, C Richter, Bruder, Joseph T

Journal:

Molecular Therapy

Année:

2008

Langue:

english

Fichier:

PDF, 566 KB

english, 2008

Multiple efficacy studies of an adenovirus-vectored foot-and-mouth disease virus serotype A24 subunit vaccine in cattle using direct homologous challenge

Schutta, Christopher, Barrera, José, Pisano, Melia, Zsak, Laszlo, Grubman, Marvin J., Mayr, Gregory A., Moraes, Mauro P., Kamicker, Barbara J., Brake, David A., Ettyreddy, Damodar, Brough, Douglas E.,

Journal:

Vaccine

Année:

2015

Langue:

english

Fichier:

PDF, 764 KB

english, 2015

Vestibular Hair Cell Regeneration and Restoration of Balance Function Induced by Math1 Gene Transfer

Staecker, Hinrich, Praetorius, Mark, Baker, Kim, Brough, Douglas E.

Journal:

Otology & Neurotology

Année:

2007

Langue:

english

Fichier:

PDF, 421 KB

english, 2007

Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo.

Kawamoto, Kohei, Ishimoto, Shin-Ichi, Minoda, Ryosei, Brough, Douglas E, Raphael, Yehoash

Journal:

The Journal of neuroscience : the official journal of the Society for Neuroscience

Année:

2003

Langue:

english

Fichier:

PDF, 466 KB

english, 2003

52. Gorilla Adenovirus Vectors for Molecular Therapeutics and Vaccines

Brough, Douglas E.

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 277 KB

english, 2015

Local adenoviral-mediated inducible nitric oxide synthase gene transfer inhibits neointimal formation in the porcine coronary stented model

Wang, Kai, Kessler, Paul D, Zhou, Zhongmin, Penn, Marc S, Forudi, Farhad, Zhou, Xiaorong, Tarakji, Khaldoun, Kibbe, Melina, Kovesdi, Imre, Brough, Douglas E, Topol, Eric J, Lincoff, A.Michael

Journal:

Molecular Therapy

Année:

2003

Langue:

english

Fichier:

PDF, 322 KB

english, 2003

Efficacy of an adenovirus-vectored foot-and-mouth disease virus serotype A subunit vaccine in cattle using a direct contact transmission model

Neilan, John G., Schutta, Christopher, Barrera, José, Pisano, Melia, Zsak, Laszlo, Hartwig, Ethan, Rasmussen, Max V., Kamicker, Barbara J., Ettyreddy, Damodar, Brough, Douglas E., Butman, Bryan T., Br

Journal:

BMC Veterinary Research

Année:

2018

Langue:

english

Fichier:

PDF, 987 KB

english, 2018

A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy

Hassan, Ahmed O., Dmitriev, Igor P., Kashentseva, Elena A., Zhao, Haiyan, Brough, Douglas E., Fremont, Daved H., Curiel, David T., Diamond, Michael S.

Journal:

Cell Reports

Année:

2019

Langue:

english

Fichier:

PDF, 3.31 MB

english, 2019

A screening-level assessment of the pollinator-attractiveness of ornamental nursery stock using a honey bee foraging assay

Sponsler, Douglas B., Grozinger, Christina M., Richardson, Rodney T., Nurse, Andrea, Brough, Dalton, Patch, Harland M., Stoner, Kimberly A.

Journal:

Scientific Reports

Année:

2020

Fichier:

PDF, 1.36 MB

2020

Hearing Preservation Following Repeated Adenovector Delivery

Pfannenstiel, Susanna C., Praetorius, Mark, Brough, Douglas E., Staecker, Hinrich

Journal:

The Anatomical Record

Année:

2020

Langue:

english

Fichier:

PDF, 777 KB

english, 2020

The Coxsackievirus-Adenovirus Receptor Protein Can Function as a Cellular Attachment Protein for Adenovirus Serotypes from Subgroups A, C, D, E, and F

Roelvink, Peter W., Lizonova, Alena, Lee, Jennifer G. M., Li, Yuan, Bergelson, Jeffrey M., Finberg, Robert W., Brough, Douglas E., Kovesdi, Imre, Wickham, Thomas J.

Journal:

Journal of Virology

Année:

1998

Fichier:

PDF, 524 KB

1998

A New Gorilla Adenoviral Vector with Natural Lung Tropism Avoids Liver Toxicity and Is Amenable to Capsid Engineering and Vector Retargeting

Lu, Zhi Hong, Dmitriev, Igor P., Brough, Douglas E., Kashentseva, Elena A., Li, Jie, Curiel, David T., Sandri-Goldin, Rozanne M.

Journal:

Journal of Virology

Année:

2020

Fichier:

PDF, 20.22 MB

2020